Products
KHDRBS3 antibody
Category:
- Catalogue No.:
- FNab04523
- Alias:
- KH domain-containing antibody, RNA-binding antibody, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like mammalian protein 2 (SLM-2)|Sam68-like phosphotyrosine protein|KHDRBS3|SALP|SLM2 antibody
- Gene Name:
- KHDRBS3
- UniProt ID:
- O75525
- Product Name
- KHDRBS3 antibody
- Catalogue No.
- FNab04523
- Gene Name
- KHDRBS3
- UniProt ID
- O75525
- Alias
- KH domain-containing antibody, RNA-binding antibody, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like mammalian protein 2 (SLM-2)|Sam68-like phosphotyrosine protein|KHDRBS3|SALP|SLM2 antibody
- Isotype
- IgG
- Form
- liquid
- Purification
- Immunogen affinity purified
- Immunogen
- KH domain containing, RNA binding, signal transduction associated 3
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
- Purity
- ≥95% as determined by SDS-PAGE
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Background
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6(PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor(PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer(By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4(AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members(PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity(By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing(By similarity). Can bind FABP9 mRNA(By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation. (Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression.
Figures for this product are not available in this catalogue.
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Dispatch Time
- About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.
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FNab04523 — KHDRBS3 antibody