NFKB1 antibody

Category:
Catalogue No.: 
FNab05702
Alias: 
Nuclear factor NF-kappa-B p105 subunit|DNA-binding factor KBF1|EBP-1|Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1|Nuclear factor NF-kappa-B p50 subunit|NFKB1 antibody
Gene Name: 
NFKB1
UniProt ID: 
P19838
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
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Product Name
NFKB1 antibody
Catalogue No.
FNab05702
Gene Name
NFKB1
UniProt ID
P19838
Alias
Nuclear factor NF-kappa-B p105 subunit|DNA-binding factor KBF1|EBP-1|Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1|Nuclear factor NF-kappa-B p50 subunit|NFKB1 antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Recommended dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100; IP: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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