RSAD2 antibody

Category:
Catalogue No.: 
FNab07504
Alias: 
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND)|Cytomegalovirus-induced gene 5 protein|Radical S-adenosyl methionine domain-containing protein 2|Virus inhibitory protein antibody, endoplasmic reticulum-associated antibody, interferon-inducible (Viperin)|RSAD2|CIG5 antibody
Gene Name: 
RSAD2
UniProt ID: 
Q8WXG1
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
Contact Us
Product Name
RSAD2 antibody
Catalogue No.
FNab07504
Gene Name
RSAD2
UniProt ID
Q8WXG1
Alias
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND)|Cytomegalovirus-induced gene 5 protein|Radical S-adenosyl methionine domain-containing protein 2|Virus inhibitory protein antibody, endoplasmic reticulum-associated antibody, interferon-inducible (Viperin)|RSAD2|CIG5 antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
radical S-adenosyl methionine domain containing 2
Recommended dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Interferon-inducible iron-sulfur(4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus(HCMV), hepatitis C virus(HCV), west Nile virus(WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus(VSV), and human immunodeficiency virus(HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase(FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells(pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor(TCR)-mediated GATA3 activation and optimal T-helper 2(Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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