Products
SMAD7 antibody
Category:
- Catalogue No.:
- FNab07999
- Alias:
- Mothers against decapentaplegic homolog 7 (MAD homolog 7 antibody, Mothers against DPP homolog 7)|Mothers against decapentaplegic homolog 8 (MAD homolog 8 antibody, Mothers against DPP homolog 8)|SMAD family member 7 (SMAD 7 antibody, Smad7 antibody, hSMAD7)|SMAD7|MADH7|MADH8 antibody
- Gene Name:
- SMAD7
- UniProt ID:
- O15105
- Product Name
- SMAD7 antibody
- Catalogue No.
- FNab07999
- Gene Name
- SMAD7
- UniProt ID
- O15105
- Alias
- Mothers against decapentaplegic homolog 7 (MAD homolog 7 antibody, Mothers against DPP homolog 7)|Mothers against decapentaplegic homolog 8 (MAD homolog 8 antibody, Mothers against DPP homolog 8)|SMAD family member 7 (SMAD 7 antibody, Smad7 antibody, hSMAD7)|SMAD7|MADH7|MADH8 antibody
- Isotype
- IgG
- Form
- liquid
- Purification
- Immunogen affinity purified
- Immunogen
- SMAD family member 7
- Recommended dilution
- WB: 1:500-1:2000
- Purity
- ≥95% as determined by SDS-PAGE
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Background
- Antagonist of signaling by TGF-beta(transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta(Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator(By similarity).
Figures for this product are not available in this catalogue.
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Dispatch Time
- About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.
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Product Inquiry
FNab07999 — SMAD7 antibody