Products
CADM1 antibody
Category:
- Catalogue No.:
- FNab10751
- Alias:
- Cell adhesion molecule 1|Immunoglobulin superfamily member 4 (IgSF4)|Nectin-like protein 2 (NECL-2)|Spermatogenic immunoglobulin superfamily (SgIgSF)|Synaptic cell adhesion molecule (SynCAM)|Tumor suppressor in lung cancer 1 (TSLC-1)|CADM1|IGSF4|IGSF4A|NECL2|SYNCAM|TSLC1 antibody
- Gene Name:
- CADM1
- UniProt ID:
- Q9BY67
- Product Name
- CADM1 antibody
- Catalogue No.
- FNab10751
- Gene Name
- CADM1
- UniProt ID
- Q9BY67
- Alias
- Cell adhesion molecule 1|Immunoglobulin superfamily member 4 (IgSF4)|Nectin-like protein 2 (NECL-2)|Spermatogenic immunoglobulin superfamily (SgIgSF)|Synaptic cell adhesion molecule (SynCAM)|Tumor suppressor in lung cancer 1 (TSLC-1)|CADM1|IGSF4|IGSF4A|NECL2|SYNCAM|TSLC1 antibody
- Isotype
- IgG
- Form
- liquid
- Purification
- Immunogen affinity purified
- Immunogen
- cell adhesion molecule 1
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
- Purity
- ≥95% as determined by SDS-PAGE
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Background
- Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer(NSCLC) cells. Interaction with CRTAM promotes natural killer(NK) cell cytotoxicity and interferon-gamma(IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly(By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Figures for this product are not available in this catalogue.
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
- Dispatch Time
- About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.
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FNab10751 — CADM1 antibody